发明名称 |
PROCESS FOR BLENDING A DIFFICULTLY SOLUBLE PHARMACEUTICAL SUBSTANCE WITH A SOLVENT USING A SYRINGE FOR APPLYING THE PROCESS |
摘要 |
The process serves to blend a difficultly soluble pharmaceutical substance filled preferably in the front chamber (2) on the cannula side of the syringe barrel (3) of a dua l- chamber syringe (1) with a solvent filled in the second chamber (4). Both chambers (2, 4) ar e separated from one another by a central stopper (8). By displacing the stopper (6) located at the plunger rod (5), first the central stopper (8) is displaced into the area of a by-pass ( 9) arranged in the wall of the syringe barrel (3) where it is stopped by lock stops (10). The solven t is then transferred via the by-pass (9) into the front chamber (2), which is sealed off by a closure system (11) arranged on the cannula side, thereby building up pressure in this chamber (2). Finally, the stopper (6) is pushed out by the built up pressure so that a portion of the solution together with a portion of the pharmaceutical substance flows back into the rear chamber (4) via the by-pass (9).
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申请公布号 |
CA2397829(A1) |
申请公布日期 |
2003.02.18 |
申请号 |
CA20022397829 |
申请日期 |
2002.08.13 |
申请人 |
ARZNEIMITTEL GMBH APOTHEKER VETTER & CO. RAVENSBURG |
发明人 |
OTTO, THOMAS;VETTER, UDO J. |
分类号 |
A61J1/05;A61M5/19;A61M5/28;A61M5/315;(IPC1-7):A61M5/178;A61M5/31 |
主分类号 |
A61J1/05 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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