PHARMACEUTICAL COMPOSITIONS, KITS AND METHODS COMPRISING COMBINATIONS OF ESTROGEN AGONISTS/ANTAGONISTS, ESTROGENS AND PROGESTINS

摘要

The present invention relates to pharmaceutical compositions, kits and methods comprising combinations of (-)-cis-6-phenyl-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-5,6,7,8-tetrahydro-naphthalene-2-ol or nontoxic pharmacologically acceptable acid addition salts thereof and estrogens. The present invention also relates to pharmaceutical compositions, kits and methods comprising combinations of (-)-cis-6-phenyl-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-5,6, 7 ,8-tetrahydro-naphthalene-2-o1 or nontoxic pharmacologically acceptable acid addition salts thereof, estrogens and progestins.