NOVEL ANALGESICS

摘要

A salt of general formula I wherein R<1>, R<2> and R<3> are independently selected from the group consisting of C1-6 alkyl groups or any two or three of R<1>, R<2> and R<3> may, together with the nitrogen to which they are attached, form a heterocyclic ring. R<4> is a selected from the group of moieties which are effective to alter the solubility of the compound in physiological fluids and pharmaceutical carries, n is an integer of 0 to 5, A is selected from hydrogen or may, with the carbon to which it is attached and with any one of R<1>, R<2> and R<3> and the nitrogen to which they are attached, form a heterocyclic ring X is a negatively charged counterion and p is the number of negative charges thereon, the number of molecules of the positively charged tertiary amino ion being equal to the integer p in any given salt. Preferably the salt is of formula II below.