发明名称 |
INTERSTRAND CROSSLINKING AGENTS FOR DNA AND COMPOUNDS THEREFOR |
摘要 |
<p>Compounds represented by the general formula (I): which two DNA strands can be interstrand-crossliked: A-L-B-X-B-L-A wherein B represents a chemical structure capable of recognizing the nucleotide sequence of DNA; A represents a chemical structure capable of binding to one of the bases of DNA; L represents a linker by which the chemical structures of A and B can be linked to each other; X represents a spacer by which the A-L-B components can be linked to each other. A method of interstrand-crosslinking DNA by using these compounds; and medicinal compositions containing interstarand-crosslinking agents of DNA. <IMAGE></p> |
申请公布号 |
EP1281711(A1) |
申请公布日期 |
2003.02.05 |
申请号 |
EP20010926081 |
申请日期 |
2001.05.01 |
申请人 |
JAPAN SCIENCE AND TECHNOLOGY CORPORATION |
发明人 |
SUGIYAMA, HIROSHI;BANDO, TOSHIKAZU;IIDA, HIROKAZU;SAITO, ISAO |
分类号 |
C07D487/10;C12N15/00;A61K31/407;A61P35/00;C07D487/04;C07D519/00;C12N15/01;C12N15/09;(IPC1-7):C07D519/00;A61K31/40 |
主分类号 |
C07D487/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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