| 摘要 |
<p>The present invention relates to a method of selective post-transcriptional silencing in a mammalian cell of the expression of an exogenous gene of viral origin. The method comprises introducing an siRNA construct into a mammalian cell where the siRNA construct is homologous to a part of the mRNA sequence of the exogenous gene. The invention also comprises an siRNA construct with a nucleotide sequence which is homologous to a part of the mRNA sequence of an exogenous gene of viral origin and to the use of such a construct as a medicament.</p> |
