摘要 |
Assays for identifying compounds that modulate, preferably inhibit bitter taste associated with the activation of hT2R4, hT2R44 and/or hT2R61 are provided. The compounds identified according to these assays should modulate, e.g., inhibit bitter taste associated with bitter tasting compounds including quinine, 6-nitrosaccharin, saccharin and/or denatonium. These compounds are useful additives for foods, beverages or medicinal preparationshaving a bitter taste. |
申请人 |
SENOMYX, INC.;PRONIN, ALEXEY;CONNOR, JUDY;TANG, HUIXIAN;KEUNG, WALTER;SERVANT, GUY;ADLER, JON, ELLIOT;O'CONNELL, SHAWN;BRUST, PAUL |
发明人 |
PRONIN, ALEXEY;CONNOR, JUDY;TANG, HUIXIAN;KEUNG, WALTER;SERVANT, GUY;ADLER, JON, ELLIOT;O'CONNELL, SHAWN;BRUST, PAUL |