发明名称 AMINEDIOLS FOR THE TREATMENT OF ALZHEIMER'S DISEASE
摘要 The present invention relates to compounds of formula (I) useful in treating Alzheiner's disease and other similar diseases. These compounds include inhibitors of the betasecretase enzyme that are useful in the treatment of Alzheiner's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.
申请公布号 WO03006453(A1) 申请公布日期 2003.01.23
申请号 WO2002US21709 申请日期 2002.07.10
申请人 ELAN PHARMACEUTICALS, INC.;PHARMACIA & UPJOHN COMPANY;SCHOSTAREZ, HEINRICH, JOSEF;CHRUSCIEL, ROBERT, ALAN 发明人 SCHOSTAREZ, HEINRICH, JOSEF;CHRUSCIEL, ROBERT, ALAN
分类号 C07D295/22;A61K31/166;A61K31/40;A61K31/421;A61K31/426;A61K31/455;A61P9/10;A61P25/00;A61P25/16;A61P25/28;C07C237/22;C07D213/82;C07D263/06;C07D263/34;C07D263/48;C07D277/20;C07D277/56;C07D295/26;C07D317/30;(IPC1-7):C07D317/30;C07D263/04;A61K31/165;A61K31/445 主分类号 C07D295/22
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