| 发明名称 |
NOVEL COMPOUNDS, THEIR PREPARATION AND USE |
| 摘要 |
The present invention relates to novel compounds that are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. Due to their pharmacological profi le the compounds of the invention may be useful for the treatment of diseases o r disorders as diverse as those related to the cholinergic system of the centr al nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by t he termination of abuse of chemical substances.
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| 申请公布号 |
CA2448913(A1) |
申请公布日期 |
2003.01.16 |
| 申请号 |
CA20022448913 |
申请日期 |
2002.07.02 |
| 申请人 |
NEUROSEARCH A/S |
发明人 |
OLSEN, GUNNAR M.;NIELSEN, ELSEBET OSTERGAARD;PETERS, DAN;AHRING, PHILIP K.;JORGENSEN, TINO DYHRING |
| 分类号 |
A61K31/439;A61K31/46;A61P1/04;A61P3/04;A61P9/00;A61P9/04;A61P9/06;A61P9/12;A61P15/00;A61P17/00;A61P21/04;A61P25/00;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P25/30;A61P25/32;A61P25/34;A61P25/36;C07D333/66;C07D409/04;C07D417/04;C07D451/02;C07D451/14;C07D453/02;C07D471/08;C07D487/04;C07D487/08;C07D521/00;(IPC1-7):C07D453/02;C07D403/04;C07D471/04;A61K31/435;A61K31/495 |
主分类号 |
A61K31/439 |
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