| 摘要 |
Mutations in Wnt receptor genes, such as FZD4, associated with hereditary human visual disorders, such as familial exudative vitreoretinopathy ("FEVR"), are disclosed along with methods of use of Wnt and/or Wnt receptor genes and proteins, including in assays for therapeutic agents useful in treating such diseases and/or ameliorating their effects as well as methods of diagnosing diseases and disorders caused by mutations in these genes. |
| 申请人 |
XENON GENETICS, INC.;UNIVERSITY OF BRITISH COLUMBIA;MACDONALD, MARCIA, L.;GOLDBERG, YIGAL, P.;HAYDEN, MICHAEL, R. |
发明人 |
MACDONALD, MARCIA, L.;GOLDBERG, YIGAL, P.;HAYDEN, MICHAEL, R. |
