| 摘要 |
<p>The present invention encompasses structures of formula (I) and the pharmaceutically acceptable non-toxic salts thereof wherein (a) represents (b), (c), (d) or (e), wherein W represents substituted or unsubstituted aryl groups; X is hydrogen, hydroxy or lower alkyl; T is hydrogen, halogen, hydroxyl, amino or alkyl; R3 is hydrogen or an organic group; R4 is hydrogen or substituted or unsubstituted organic substituent; R5 and R6 represent organic, and inorganic substituents; and n is 1, 2, 3, or 4. These compounds are highly selective agonists, antagonists or inverse agonists for GABA brain receptors or prodrugs of agonists, antagonists or inverse agonists for GABA brain receptors. These compounds are useful in the diagnosis and treatment of anxiety, sleep and seizure disorders, overdose with benzodiazepine drugs and for enhancement of memory.</p> |
