| 发明名称 |
Thiol derivatives with metallopeptidase inhibitory activity |
| 摘要 |
<p>Compounds of formula (I), wherein R, R1, R2, and R3 have the meanings reported in the description, processes for their preparation and pharmaceutical compositions which contain them as active ingredients are described. The compounds of formula (I) are endowed with a mixed ACE-inhibitory and NEP-inhibitory activity and are useful in the treatment of cardiovascular diseases.</p> |
| 申请公布号 |
SK282977(B6) |
申请公布日期 |
2003.01.09 |
| 申请号 |
SK19980000889 |
申请日期 |
1996.12.17 |
| 申请人 |
ZAMBON GROUP S. P. A. |
发明人 |
PELLACINI FRANCO;FANTUCCI MARIO;NORCINI GABRIELE;ROMAGNANO STEFANO;SANTANGELO FRANCESCO;SEMERARO CLAUDIO |
| 分类号 |
A61K31/00;A61K31/34;A61K31/341;A61K31/38;A61K31/381;A61K31/425;A61K31/426;A61K31/44;A61K31/4427;A61K31/4439;A61K31/495;A61K31/505;A61P9/00;A61P43/00;C07D213/55;C07D239/26;C07D241/12;C07D277/20;C07D277/30;C07D307/54;C07D333/24;C07D417/12;(IPC1-7):C07D277/30 |
主分类号 |
A61K31/00 |
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