| 发明名称 |
High throughput knockout constructs in yeast by homologous recombination |
| 摘要 |
The present invention is directed to methods for producing gene targeting constructs by homologous recombination using mouse genomic libraries arrayed in yeast shuttle vectors. The invention is also directed to methods of using targeting constructs made by the methods to generate transgenic animals.
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| 申请公布号 |
US6503712(B1) |
申请公布日期 |
2003.01.07 |
| 申请号 |
US20000569975 |
申请日期 |
2000.05.10 |
| 申请人 |
AMGEN INC. |
发明人 |
THUKRAL SUSHIL K. |
| 分类号 |
C12N1/21;C12N15/10;C12N15/70;C12N15/81;C12N15/85;(IPC1-7):C12Q1/68;C07H21/02;C07H21/04;C12N15/74 |
主分类号 |
C12N1/21 |
| 代理机构 |
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