发明名称 |
Separation matrix having a ligand density gradient |
摘要 |
The present invention relates to a separation matrix comprised of ligands coupled to the surfaces of a porous support, such as one or more porous particles, wherein the ligands provide at least one chemical gradient within the support. In the most advantageous embodiment, the chemical gradient is a ligand density gradient. The invention also relates to a method of providing a separation matrix comprising ligands coupled to the surfaces of a porous support, in which method at least one ligand density gradient is provided by solvent-controlled diffusion of at least one reagent into the porous support. |
申请公布号 |
US8070958(B2) |
申请公布日期 |
2011.12.06 |
申请号 |
US20100692671 |
申请日期 |
2010.01.25 |
申请人 |
BERGSTROM JAN;GLAD GUNNAR;JOHANSSON BO-LENNART;LJUNGLOF ANDERS;MALOISEL JEAN-LUC;GE HEALTHCARE BIO-SCIENCES AB |
发明人 |
BERGSTROM JAN;GLAD GUNNAR;JOHANSSON BO-LENNART;LJUNGLOF ANDERS;MALOISEL JEAN-LUC |
分类号 |
B01D15/08;B01D;B01J20/28;B01J20/286;B01J20/30;B01J20/32;C02F1/28 |
主分类号 |
B01D15/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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