MICROFABRICATED SEPARATION DEVICE EMPLOYING A VIRTUAL WALL FOR INTERFACING FLUIDS

摘要

A fluid interface port (15) in a separation device for separating a sample into different components is provided. The separation device includes an array of separation channels (500) and the fluid interface port (17) comprises an opening formed in the side wall of a separation channel (500) sized and dimensioned to form a virtual wall (15) when the separation channel is filled with a separation medium (20). The fluid interface port (17) is utilized to introduce a liquid sample (19a) into the separation medium (20). The interface ports (17) formed in the array of separation channels (500) are organized into one or more sample injectors. A cathode reservoir is multiplexed with one or more separation channels. To complete an electrical path, an anode reservoir which is common to some or all separation channels (500) is also provided.