| 摘要 |
<p>An immune response in an organism is controlled by administering to said organism a therapeutically effective amount of a compound which binds to a galectin. In specific instances the compound is selected to bind to galectin-1 or galectin-3. Some therapeutic materials comprise natural or synthetic polymers having galactose or arabinose terminated side chains pendent therefrom. A group of preferred therapeutic compounds comprise modified pectins or other materials having a substantially demethoxylated rhamnogalacturan backbone having rhamnose residues interrupting the backbone. One therapeutic material includes a first functional portion which binds to the carbohydrate binding portion of a galectin, and a second functional portion which is operable denature the galectin protein.</p> |
