发明名称 |
METHODS OF TREATING ALZHEIMER'S DISEASE |
摘要 |
Disclosed are methods for treating Alzheimer's disease, and other diseases, and/or inhibiting beta-secretase enzyme, and/or inhibiting deposition of A beta peptide in a mammal, by use of hydrazine compounds of formula (I) where in the variables R1-R9 are defined herein.
|
申请公布号 |
CA2449948(A1) |
申请公布日期 |
2002.12.19 |
申请号 |
CA20022449948 |
申请日期 |
2002.06.07 |
申请人 |
PHARMACIA & UPJOHN COMPANY;ELAN PHARMACEUTICALS, INC. |
发明人 |
CHRUSCIEL, ROBERT ALAN;SCHOSTAREZ, HEINRICH |
分类号 |
C07D295/20;A61K31/137;A61K31/165;A61K31/166;A61K31/17;A61K31/325;A61K31/341;A61K31/40;A61K31/41;A61K31/4164;A61K31/426;A61K31/44;A61K31/4402;A61K31/4406;A61K31/47;A61K31/535;A61K31/5375;A61K31/54;A61K31/66;A61K31/7068;A61K45/06;A61P9/10;A61P25/00;A61P25/28;A61P43/00;C07C243/10;C07D213/40;C07D213/56;C07D213/79;C07D215/48;C07D233/64;C07D257/04;C07D277/20;C07D277/56;C07D307/12;C07D401/12;(IPC1-7):A61K31/535 |
主分类号 |
C07D295/20 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|