| 发明名称 |
CLONING OF THE BIOSYNTHETIC PATHWAY GENES FOR CHLORTETRACYCLINE PRODUCTION FROM STREPTOMYCES AUREOFACIENS AND THEIR EXPRESSION IN STEPTOMYCES LIVIDANS |
| 摘要 |
The present invention relates to the cloning, isolation and DNA (isolated fragment from Streptomyces aureofaciens) which directs the synthesis of tetracycline and chlortetracycline, in a heterologous host such as Streptomyces lividans. The claimed plasmids are isolated by screening a cosmid library, constructed in Escherichia coli, for the expression of tetracycline resistance in S. lividans.
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| 申请公布号 |
CA2047833(C) |
申请公布日期 |
2002.12.17 |
| 申请号 |
CA19912047833 |
申请日期 |
1991.07.24 |
| 申请人 |
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发明人 |
LOTVIN, JASON A.;RYAN, MICHAEL J.;STRATHY, NANCY |
| 分类号 |
C12N15/09;C12N1/21;C12N15/52;C12N15/76;C12P29/00;C12Q1/18;C12R1/19;C12R1/465;C12R1/485;(IPC1-7):C12N15/52;C12Q1/68 |
主分类号 |
C12N15/09 |
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