<i>Caulobacter</i> optimized for use in expression of heterologous peptides as part of a hybrid <i>Caulobacter</i> S-layer protein are provided as well as methods for producing such <i>Caulobacter</i>. <i>Caulobacter</i> of this invention are deficient in a native <i>Caulobacter</i> protease that cleaves hybrid S-layer proteins. Also provided are <i>Caulobacter</i> libraries and methods for sorting such libraries using cell sorting technology such as FACS.
申请公布号
WO02095039(A1)
申请公布日期
2002.11.28
申请号
WO2002CA00722
申请日期
2002.05.22
申请人
THE UNIVERSITY OF BRITISH COLUMBIA;SMIT, JOHN;NOMELLINI, JOHN, F.;BINGLE, WADE, H.