发明名称 METHOD FOR THE PREPARATION OF 1-BENZOTRIAZOLYL CARBONATE ESTERS OF WATER SOLUBLE POLYMERS.
摘要 The present invention provides a biologically active conjugate, obtainable by reacting an amino acid derivative of the following structure wherein PEG is poly(ethylene glycol) and Z is selected from the group consisting ofH, N-succinimidyl, or 1-benzotriazolyl, with a protein.
申请公布号 EP1259563(A2) 申请公布日期 2002.11.27
申请号 EP20000986602 申请日期 2000.12.18
申请人 SHEARWATER CORPORATION 发明人 KOZLOWSKI, ANTONI
分类号 C12N9/96;A61K47/48;C08F8/30;C08G65/325 主分类号 C12N9/96
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