发明名称 Heterocyclic benzenesulphonamide compounds as bradykinine antagonists
摘要 The invention concerns compounds selected among the group consisting of (i) compounds of formula (I) wherein: Het1 represents a nitrogenous heterocycle with 5 apices, in particular imidazole, pyrazole, or triazole; Het2 represents a nitrogenous heterocycle with 4, 5 or 6 apices, selected among the heterocycles: (II) wherein R1 and R2 are defined as mentioned in the description; and (ii) their additive salts. The invention also concerns the method for preparing said compounds and their use in therapy, in particular for treating pathologies involving bradykinine.
申请公布号 US6479515(B1) 申请公布日期 2002.11.12
申请号 US20010889965 申请日期 2001.07.24
申请人 FOURNIER INDUSTRIE ET SANTE 发明人 DODEY PIERRE;BARTH MARTINE;BONDOUX MICHEL
分类号 A61P29/00;C07D521/00;(IPC1-7):A61K31/470;C07D401/14 主分类号 A61P29/00
代理机构 代理人
主权项
地址