发明名称 |
3-indolyl-4-phenyl-1H-pyrrole-2,5-dione derivatives as inhibitors of glycogen synthase kinase-3beta |
摘要 |
This invention relates to inhibitors of glycogen synthase kinase-3beta, methods of treating diseases characterized by an excess of Th2 cytokines, and to 3-indolyl-4-phenyl-1H-pyrrole-2,5-dione derivatives of Formula (I):that are inhibitors of glycogen synthase kinase -3beta, pharmaceutical compositions containing them, methods for their use and methods for preparing these compounds.
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申请公布号 |
US6479490(B2) |
申请公布日期 |
2002.11.12 |
申请号 |
US20010916706 |
申请日期 |
2001.07.27 |
申请人 |
SYNTEX (U.S.A.) LLC |
发明人 |
GONG LEYI;GRUPE ANDREW;PELTZ GARY ALLEN |
分类号 |
A61K31/404;A61K31/4178;A61K31/454;A61K31/5377;A61K31/695;A61P3/04;A61P3/10;A61P7/02;A61P9/10;A61P11/02;A61P11/06;A61P15/00;A61P17/02;A61P25/00;A61P25/18;A61P25/28;A61P35/00;A61P37/02;A61P37/08;A61P43/00;C07D401/14;C07D403/04;C07D403/14;C07D405/14;(IPC1-7):A61K31/535;A61K31/40;C07D413/00;C07D401/60;C07D209/02 |
主分类号 |
A61K31/404 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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