| 发明名称 |
Humanized antibody and uses thereof |
| 摘要 |
A humanized antibody framework motif is described. Preferably, the motif is encoded by the VH gene of K5B8 and the VL gene of TR1.6. This humanized antibody preferably contains the variable region of a tat antibody.
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| 申请公布号 |
US6479284(B1) |
申请公布日期 |
2002.11.12 |
| 申请号 |
US20000660169 |
申请日期 |
2000.09.12 |
| 申请人 |
DANA-FARBER CANCER INSTITUTE, INC.;AVANT IMMUNOTHERAPEUTICS, INC.;CHIRON CORPORATION |
发明人 |
MARASCO WAYNE A.;LAVECCHIO JOYCE;MHASHILKAR ABNER;RAMSTEDT URBAN;RING DAVID;EBERHARDT BRIDGET;PORTER-BROOKS JULIE |
| 分类号 |
C12N15/09;A61K39/395;A61K39/42;A61K48/00;A61P31/18;A61P37/02;A61P37/04;C07K16/08;C07K16/10;C12P21/08;(IPC1-7):C12N5/06;G01N33/53;C12P21/04;C07K16/00 |
主分类号 |
C12N15/09 |
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