ABC EXPRESSION PROMOTERS

摘要

ABC-A1 mRNA expression promoters, LXR.alpha. mRNA expression promoters, ABC- G1 mRNA expression promoters, cholesterol transport promoters and cholesteryl ester accumulation inhibitors containing PPAR.delta. modulators such as pioglitazone; ABC-G1 mRNA expression promoters containing PPAR.delta. modulators; or ACAT-1 mRNA expression promoters and CEH mRNA expression promoters containing PPAR.delta. modulators such as pioglitazone. These agen ts are excellent in the ability to control cholesterol distribution in vivo and have low toxicity.