Breath activated nasal delivery devices comprising a breath analyser

摘要

A nasal delivery device for delivering at least one substance to the nasal cavity of a subject, including a delivery unit 20 comprising a nosepiece 21 for fitting to the nostril of a subject, a mouthpiece 23 through which the subject exhales, a breath analyser 29 for analysing the concentration of at least one component in exhaled air from an exhalation breath and a substance supply unit 31 for supplying at least one substance, the substance supply unit 31 including a control unit 35 for controlling the same to control supply of the at least one substance in response to the detected concentration. In another aspect, a nasal resistance measurement device and a method of determining a flow resistance of a nasal airway of a subject.