发明名称 TOPOISOMERASE I SELECTIVE CYTOTOXIC SUGAR DERIVATIVES OF INDOLOPYRROLOCARBAZOLES
摘要 The present invention relates to fluoro sugar and other sugar derivatives of indolopyrrolocarbazoles, their salts and hydrates, which exhibit selective topoisomerase I (topo I) activity, are useful in inhibiting the proliferatio n of tumor cells and exhibit an antitumor effect, as well as processes for the ir preparation.
申请公布号 CA2441412(A1) 申请公布日期 2002.10.03
申请号 CA20022441412 申请日期 2002.03.22
申请人 BRISTOL-MYERS SQUIBB COMPANY 发明人 NAIDU, NARASIMHULU B.;ST-LAURENT, DENIS ROBERT;BEAULIEU, FRANCIS;RUEDIGER, EDWARD H.;SAULNIER, MARK G.;STOFFAN, KAREN;ZIMMERMAN, KURT;BACHAND, CAROL;FRENNESSON, DAVID B.;LONG, BYRON HEPLER;BALUSUBRAMANIAN, NEELAKANTAN
分类号 C12P19/28;A61K31/7052;A61P35/00;A61P43/00;C07H15/00;C07H19/00;C07H19/23;C12N1/12;C12P17/10;C12P17/18;(IPC1-7):C07D495/14;A61K45/06;C07D487/14;C07D491/14;A61K31/40;A61K31/403;A61K31/404 主分类号 C12P19/28
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