发明名称 |
Method for detecting chemical interactions between naturally occurring biological analyte molecules |
摘要 |
A method of using micromechanical devices as sensors for detecting chemical interactions between naturally occurring bio-polymers which are non-identical binding partners is provided. The method is useful whether the reactions occur through electrostatic forces or other forces. Induced stress, heat, or change in mass is detected where a binding partner is placed on a cantilever for possible reaction with an analyte molecules (i.e., a non-identical binding partner). The method is particularly useful in determining DNA hybridization but may be useful in detecting interaction in any chemical assay.
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申请公布号 |
US2002137084(A1) |
申请公布日期 |
2002.09.26 |
申请号 |
US20020072414 |
申请日期 |
2002.02.05 |
申请人 |
QUATE CALVIN F.;TRULSON MARK O.;MANALIS SCOTT R.;FORMAN JONATHAN E. |
发明人 |
QUATE CALVIN F.;TRULSON MARK O.;MANALIS SCOTT R.;FORMAN JONATHAN E. |
分类号 |
C12Q1/68;G01N33/543;(IPC1-7):C12Q1/68;G01N33/53;C12M1/34 |
主分类号 |
C12Q1/68 |
代理机构 |
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