| 摘要 |
<p>The invention relates to medicine, pharmocology and to the chemical and pharmaceutical industry. The aim of the invention is to develop a new medicinal preparation having high activity and having a large range of the above mentioned non-specific pharmacological action, and a production method for all presently known dosage forms. The novelty of the invention lies in a biologically active part of the preparation which contains a mixture of acridoneacetic acid or the derivatives thereof with monosubstituted ethers of monosaccharides, the biologically active part being heat treated together with a pharmaceutically acceptable carrier at temperatures ranging from 80 °C to 120 °C. The medicinal preparation containing ANANDIN exhibits higher efficiency. ANANDIN is embodied in the form of a mixture of N- acridoneacetic acid (glucoaminopropylcarbacridone) and 3-0 (N,N-dimethylamino-n-propyl)-1.2:5.6- di-O-isopropylidene-α, D-glucofuranose (dimethylaminopropylglucofuranose). The inventive medicinal preparation is embodied in the form of all known dosage forms. Six series of examples for producing the preparation and the dosage forms thereof, detailed information on the experimental estimate of all biological activities enumerated in the title provided with 7 tables of comparative measuring are also disclosed. The results demonstrate that a new, easily produced, stable, medicinal preparation usable for all dosage forms is created. The biological activity of said preparation exceeds the biological activity of analogous preparations, and the range of pharmacological action thereof is non-specific and unusually large.</p> |
