TISSUE ENGINEERING ENHANCED BY THE TRANSFER OF A GROWTH FACTOR GENE
摘要
Tissue engineered constructs including a matrix and cells transfected with a gene for a growth factor. The constructs may be implanted into a tissue site, where the growth factor gene enhances a metabolic function furthering integration of the construct in the tissue site. If the matrix is biodegradable, the metabolic result may include resorption of the matrix and replacement with tissue synthesized at least in part by the transfected cells.
申请公布号
WO02074912(A2)
申请公布日期
2002.09.26
申请号
WO2002US07805
申请日期
2002.03.14
申请人
MASSACHUSETTS INSTITUTE OF TECHNOLOGY
发明人
MADRY, HENNING;VUNJAK-NOVAKOVIC, GORDANA;TRIPPEL, STEPHEN, B.;FREED, LISA, E.;LANGER, ROBERT