| 摘要 |
The invention relates to a method, which identifies genetic toxic stress in living mammalian cells by the detection of all previously documented types of DNA recombination and also identifies mutations in response to noxa. The identification is based on the detection of fluorescence from intact autofluorescent proteins or of luminescence by means of intact bioluminescent enzymes or enzymes that convert chemical luminescent substrates. Said identification is characterised by a short reaction time of approximately one hour and permits the transfer of the test system to different mammalian cells and to living experimental animals.
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