发明名称 |
3-ETHYL-, 3-PROPYL- OR 3-BUTYL-CHROMAN AND -THIOCHROMAN DERIVATIVES |
摘要 |
<p>A compound having the following general formula (1): <CHEM> in which R1 represents an ethyl group, etc.; R2 represents a hydrogen atom, etc.; R3 represents a C1-C5 perhalogenoalkyl group, etc.; each of R4 and R5 independently represents a hydrogen atom, etc.; X represents an oxygen atom or a sulfur atom; m represents an integer of 2 to 14; and n represents an integer of 2 to 7; or an enantiomer of the compound, or a hydrate or a pharmaceutically acceptable salt of the compound or its enantiomer is advantageous in pharmaceutical use because of its anti-estrogenic activity.</p> |
申请公布号 |
EP1241167(A1) |
申请公布日期 |
2002.09.18 |
申请号 |
EP20000981680 |
申请日期 |
2000.12.13 |
申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA |
发明人 |
JO, JAECHON;KIM, JONGMIN;AHN, SUNGOH;CHOI, JAEYOUNG;MORIKAWA, KAZUMI;KANBE, YOSHITAKE;NISHIMOTO, MASAHIRO;KIM, MYUNGHWA |
分类号 |
A61P5/32;A61P35/00;C07D311/58;C07D335/06;(IPC1-7):C07D311/58;A61K31/382;A61K31/352 |
主分类号 |
A61P5/32 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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