发明名称 Polynucleotides encoding thrombin receptor homologs
摘要 The present invention provides nucleotide and amino acid sequences that identify and encode a novel thrombin receptor homolog (TRH) expressed in human liver. The present invention also provides for antisense molecules to the nucleotide sequences which encode TRH, diagnostic tests based on TRH encoding nucleic acid molecules, expression vectors for the production of purified TRH, antibodies capable of binding specifically to TRH, hybridization probes or oligonucleotides for the detection of TRH-encoding nucleotide sequences, genetically engineered host cells for the expression of TRH, and antagonists, antibodies and inhibitors with specific binding activity for the polypeptide TRH.
申请公布号 US2002128443(A1) 申请公布日期 2002.09.12
申请号 US20010997522 申请日期 2001.11.28
申请人 INCYTE PHARMACEUTICALS, INC. 发明人 COLEMAN ROGER;AU-YOUNG JANICE;BANDMAN OLGA;SEILHAMER JEFFREY J.
分类号 C12N15/09;A61K31/70;A61K38/00;A61K39/395;A61K48/00;A61P43/00;C07K14/705;C12N15/12;C12P21/02;C12Q1/68;G01N33/53;(IPC1-7):C07K14/705;C07H21/04;C12N5/06 主分类号 C12N15/09
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