Substituted amides, their production and their use

摘要

Amides of the general formula Iand their tautomeric and isomeric forms, possible enantiomeric and diastereomeric forms, as well as possible physiologically tolerable salts, in which the variables have the following meanings:R1 [sic] can be C1-C6-alkyl, phenyl, naphthyl, quinolyl, pyridyl, pyrimidyl, pyridazyl, quinazolyl and quinoxalyl, where the rings can additionally be substituted by up to 2 radicals R4 [sic], andR2 [sic] is -(CH2)m-R8 [sic], where R8 [sic] can be phenyl, cyclohexyl- or indolyl and m=1 to 6, andX is a bond, -CH2-, -CH2CH2-, -CH=CH-, -C=C-, -CONH-, -SO2NH- [sic], and and [sic]R1-X [sic] together are also andR3 [sic] is hydrogen and CO-NR6R7 [sic],R4 [sic] is hydrogen, C1-C4-alkyl [sic], which is branched and unbranched, and -O-C1-C4-alkyl [sic];R5 [sic] is hydrogen, C1-C4-alkyl [sic], which is branched or unbranched, and -O-C1-C4-alkyl [sic];R6 [sic] is hydrogen, C1-C6-alkyl, which is branched and unbranched, andR7 [sic] is hydrogen, C1-C6-alkyl, which is branched or unbranched, andn is is [sic] a number 0, 1 or 2.