| 摘要 |
<p>Compounds of formula (i) and of formula (ii), wherein the symbols have the meaning disclosed in the claims, specifically or selectively modulate α2A adrenergic receptors and as such are useful for alleviating chronic pain and allodynia and have no or only minimal cardiovascular and/or sedatory activity. The invention also relates to a method of activating α2B or α2C adrenergic receptors in a mammal by administering a compound that has α2Bor α2C adrenergic receptor activity and has no significant α2A agonist activity.</p> |
