| 发明名称 |
Method and means for producing high titer, safe, recombinant lentivirus vectors |
| 摘要 |
Lentiviral vectors modified at the 5' LTR or both the 5' and 3' LTR's are useful in the production of recombinant lentivirus vectors. Such vectors can be produced in the absence of a functional tat gene. Multiple transformation of the host cell with the vector carrying the transgene enhances virus production. |
| 申请公布号 |
AU751985(B2) |
申请公布日期 |
2002.09.05 |
| 申请号 |
AU19990018034 |
申请日期 |
1998.12.11 |
| 申请人 |
CELL GENESYS, INC. |
发明人 |
LUIGI NALDINI;THOMAS DULL;DEBORAH A FARSON;ROCHELLE WITT |
| 分类号 |
C12N15/09;A61K48/00;C07K14/16;C12N5/10;C12N7/01;C12N15/49;C12N15/867;(IPC1-7):C12N15/49;C12N15/64;C12N15/86 |
主分类号 |
C12N15/09 |
| 代理机构 |
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