发明名称 |
Lactose-free, non-hygroscopic and anhydrous pharmaceutical compositions of descarboethoxyloratadine |
摘要 |
Stable pharmaceutical compositions of descarboethoxyloratadine (DCL), a metabolic derivative of loratadine, for the treatment of allergic rhinitis and other histamine-induced disorders are disclosed. The compositions are formulated to avoid the incompatibility between DCL and reactive excipients such as lactose and other mono- and di-saccharides. Disclosed compositions include lactose-free, non-hygroscopic and anhydrous stable pharmaceutical compositions of DCL.
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申请公布号 |
US2002123504(A1) |
申请公布日期 |
2002.09.05 |
申请号 |
US20020082685 |
申请日期 |
2002.02.25 |
申请人 |
SEPRACOR INC. |
发明人 |
REDMON MARTIN P.;BUTLER HAL T.;WALD STEPHEN A.;RUBIN PAUL D. |
分类号 |
C07D401/04;A61K9/20;A61K31/445;A61K31/4545;A61K31/60;A61P11/02;A61P17/04;A61P27/02;A61P27/16;A61P29/00;A61P37/08;A61P43/00;(IPC1-7):A61K31/473;A61K31/192 |
主分类号 |
C07D401/04 |
代理机构 |
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代理人 |
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地址 |
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