Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation

摘要

Compounds of the following formula
<Chemistry id="chema01" num="0001"><Image id="ia01" he="52" wi="81" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" /></Chemistry> wherein R<Sub>3</Sub> is OC(O)R<Sub>1</Sub>,
<UnorderedLists id="ula01" listStyle="none"><ListItem>where R<Sub>1</Sub> is selected from the group consisting of C<Sub>1</Sub>-C<Sub>17</Sub> alkyl, C<Sub>2</Sub>-C<Sub>9</Sub> alkenyl, C<Sub>2</Sub>-C<Sub>3</Sub> alkynyl; and</ListItem></UnorderedLists> wherein M is selected from the group consisting of C(O)R<Sub>3</Sub>, SO<Sub>2</Sub>R<Sub>9</Sub>,
<UnorderedLists id="ula02" listStyle="none"><ListItem>where R<Sub>3</Sub> is selected from the groups consisting of H, C<Sub>3</Sub>-C<Sub>6</Sub> cycloalkyl, alkoxyalkyl, haloalkyl, alkoxyalkenyl, haloalkenyl, alkoxyalkynyl, haloalkynyl, substituted and unsubstituted arylalkyl, substituted and unsubstituted arylalkenyl, substituted and unsubstituted arylalkynyl, substituted and unsubstituted aryl, substituted and unsubstituted heteroaryl, C<Sub>1</Sub>-C<Sub>6</Sub> alkoxy, C<Sub>3</Sub>-C<Sub>5</Sub> cycloalkoxy, C<Sub>2</Sub>-C<Sub>5</Sub> haloalkoxy, C<Sub>2</Sub>-C<Sub>6</Sub> alkenyloxy, C<Sub>2</Sub>-C<Sub>6</Sub> haloalkenyloxy, C<Sub>2</Sub>-C<Sub>5</Sub> alkynyloxy, C<Sub>2</Sub>-C<Sub>6</Sub> haloalkynyloxy, C<Sub>1</Sub>-C<Sub>5</Sub> thioalkoxy, substituted and unsubstituted arylalkoxy, substituted and unsubstituted arylalkenyloxy, substituted and unsubstituted arylalkynyloxy, substituted and unsubstituted aryloxy, substituted and unsubstituted heteroaryloxy, amino unsubstituted or substituted with one or two C<Sub>1</Sub>-C<Sub>6</Sub> alkyl groups, and</ListItem><ListItem>where R<Sub>9</Sub> is selected from the group consisting of C<Sub>2</Sub>-C<Sub>5</Sub> alkenyl, C<Sub>3</Sub>-C<Sub>5</Sub> alkynyl, C<Sub>3</Sub>-C<Sub>6</Sub> cycloalkyl, aryl, or heteroaryl</ListItem></UnorderedLists> which are useful as antifungal agents.