PREFILLED SYRINGE PHARMACEUTICAL PREPARATION OF ELCATONIN

摘要

PROBLEM TO BE SOLVED: To obtain a prefilled syringe pharmaceutical preparation of elcatonin having stability and safe for human bodies. SOLUTION: This prefilled syringe pharmaceutical preparation of the elcatonin is filled with an aqueous solution containing the elcatonin as an active ingredient and is characterized in that the amount of elution into the aqueous solution is <=2% expressed in terms of area ratio measured by high-performance liquid chromatography. The prefilled syringe pharmaceutical preparation of the elcatonin is filled with the aqueous solution containing the elcatonin as the active ingredient and is characterized in that the volume of a gap part is <=0.2 when the volume occupied by the aqueous solution is 1. The prefilled syringe pharmaceutical preparation of the elcatonin comprises the syringe having a silicone at <=3 wt./vol.% concentration applied to the inner surface and filled with the aqueous solution containing the elcatonin as the active ingredient.