| 发明名称 |
GENE DELIVERY FORMULATIONS AND METHODS FOR TREATMENT OF ISCHEMIC CONDITIONS |
| 摘要 |
The present inventors have developed a novel approach for efficient delivery of angiogenic factors to the cardiac and peripheral vasculature that avoids problems with toxicity inherent to existing delivery technologies. Vectors carrying coding sequences for Del-1 or VEGF, or both, can be formulated with poloxamers or other polymers for delivery into ischemic tissue and delivered to the heart by retrograde venous perfusion.
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| 申请公布号 |
CA2426582(A1) |
申请公布日期 |
2002.08.08 |
| 申请号 |
CA20012426582 |
申请日期 |
2001.10.19 |
| 申请人 |
VALENTIS, INC. |
发明人 |
WANG, JIJUN;THIESSE, MARY L.;YOUNG, STEWART;COLEMAN, MICHAEL E.;NORDSTROM, JEFFREY L.;MACLAUGHLIN, FIONA |
| 分类号 |
C12N15/09;A61K35/76;A61K38/00;A61K38/17;A61K38/18;A61K38/19;A61K47/18;A61K47/32;A61K47/34;A61K47/42;A61K48/00;A61P9/00;A61P9/10;C07K14/475;C12N15/87;(IPC1-7):A61K9/14;C12N15/63 |
主分类号 |
C12N15/09 |
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