| 发明名称 |
Calcium-independent negative regulation by CD81 of receptor signaling |
| 摘要 |
Calcium independent CD81 inhibition of IgE-mediated degranulation in mast cells, particularly through the FcgammaRIII and FCepsiRI receptors, is described, as well as methods of inhibiting allergic processes.
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| 申请公布号 |
US6423501(B2) |
申请公布日期 |
2002.07.23 |
| 申请号 |
US19970954279 |
申请日期 |
1997.10.20 |
| 申请人 |
BETH ISRAEL DEACONESS MEDICAL CENTER |
发明人 |
FLEMING TONY;KINET JEAN-PIERRE |
| 分类号 |
A61K38/00;C07K14/705;C07K16/28;(IPC1-7):G01N33/53;C07K14/52;C12N15/00 |
主分类号 |
A61K38/00 |
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