发明名称 |
Organo luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes |
摘要 |
A semiconductor nanocrystal compound is described capable of linking to an affinity molecule. The compound comprises (1) a semiconductor nanocrystal capable of emitting electromagnetic radiation and/or absorbing energy, and/or scattering or diffracting electromagnetic radiation-when excited by an electromagnetic radiation source or a particle beam; and (2) at least one linking agent, having a first portion linked to the semiconductor nanocrystal and a second portion capable of linking to an affity molecule. The compound is linked to an affinity molecule to form a semiconductor nanocrystal probe capable of bonding with a detectable substance. Subsequent exposure to excitation energy will excite the semiconductor nanocrystal in he probe, causing the emission of electromagnetic radiation. Further described are processes for respectively: making the semiconductor nanocrystal compound; making the semiconductor nanocrystal probe; and using the probe to determine the presence of a detectable substance in a material.
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申请公布号 |
US6423551(B1) |
申请公布日期 |
2002.07.23 |
申请号 |
US19990349833 |
申请日期 |
1999.07.08 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
WEISS SHIMON;BRUCHEZ, JR. MARCEL;ALIVISATOS PAUL |
分类号 |
C12Q1/68;G01N33/533;G01N33/542;G01N33/543;G01N33/58;G01Q70/08;G01Q70/18;(IPC1-7):G01N33/543 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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