A NOVEL FIBRINOLYTIC ENZYME THE POLYNUCLEOTIDE ENCODING SAID POLYPEPTIDE AND THE USE THEREOF

摘要

The invention discloses a new kind of fibrinolytic enzyme - fibrinolytic enzyme Z from earthworm, polynucleotide encoding said fibrinolytic enzyme Z and a process for producing said fibrinolytic enzyme Z by recombinant technology. It also discloses the method of applying the fibrinolytic enzyme Z for the treatment of various kinds of diseases, such as thrombo-embolia disease. In addition, the medicines composition which contains earthworm fibrinolytic enzyme Z is also disclosed.