SURFACE-FUNCTIONALISED CARRIER MATERIAL, METHOD FOR THE PRODUCTION THEREOF AND SOLID PHASE SYNTHESIS METHOD

摘要

The invention relates to a novel surface-functionalised carrier material comprising a polymer surface and at least one linker compound according to general formula (I), which is bonded to said surface in a covalent manner. In formula (I), P represents the polymer surface; R<2> represents OR<4> or NR<4>R<5>; R<1>, R<4> and R<5> independently represent H, an alkyl group or an aryl group; R<3> represents H, an alkyl group, an aryl group, an acyl group, an alkoxycarbonyl group or an aryloxycarbonyl group; and the alkyl, aryl, acyl, alkoxycarbonyl and/or aryloxycarbonyl groups of the radicals R<1>, R<3>, R<4> and R<5> are independently substituted or unsubstituted. The inventive material can be very easily produced by means of photochemical coupling and is used for the solid phase synthesis of amino acids, peptides, proteins or molecules comprising at least one peptide structural unit.