发明名称 |
Composition and pharmaceutical dosage form for colonic drug delivery using polysaccharides |
摘要 |
A colonic drug delivery composition contains a first polysaccharide and a second polysaccharide wherein both polysaccharide are degradable by colonic enzymes and are mixed at a environmental pH of about 7 or above, without use of a cross-linking agent. A colon selective pharmaceutical composition and dosage form for oral delivery of a drug, diagnostic reagent, or mixture thereof includes the drug, diagnostic reagent, or mixture thereof in contact with the polysaccharide composition. A method of preparing such a colonic drug delivery composition and the colon selective pharmaceutical composition and dosage from are also disclosed.
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申请公布号 |
US6413494(B1) |
申请公布日期 |
2002.07.02 |
申请号 |
US19990318579 |
申请日期 |
1999.05.25 |
申请人 |
SAMYANG CORPORATION |
发明人 |
LEE SEUNG SEO;LIM CHANG BAEG;PAI CHAUL MIN;LEE SUJUNG;PARK IN;SEO MOON GUN;PARK HEENAM |
分类号 |
A61K47/36;A61K9/22;A61K9/28;A61K9/36;A61K9/48;A61K9/50;A61K9/51;A61K9/62;A61K31/138;A61K31/192;A61K31/196;A61K31/4164;A61K31/435;A61K31/445;A61K31/454;A61K31/506;A61K31/519;A61K31/573;A61K31/70;A61K38/00;A61K38/11;A61K38/22;A61K38/23;A61K38/27;A61K38/28;A61P1/00;C08L5/06;(IPC1-7):A61K49/00;A61K9/00;A61K31/715 |
主分类号 |
A61K47/36 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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