| 发明名称 |
PHARMACEUTICAL FORMULATIONS AND METHODS COMPRISING INTRANASAL MORPHINE |
| 摘要 |
<p>The present invention relates to a pharmaceutical formulation for intranasal administration comprising morphine or pharmaceutically acceptable salt thereof at a pH from about 3.0 to about 7.0. Such formulations provide enhanced absorption of morphine or pharmaceutically acceptable salts thereof. In one embodiment, the present invention provides a method for eliciting an analgesic or anaesthetic response in a mammal which includes nasally administering a therapeutically effective amount of morphine or pharmaceutically acceptable salt thereof at a pH from about 3.0 to about 7.0. <IMAGE></p> |
| 申请公布号 |
SK18172001(A3) |
申请公布日期 |
2002.07.02 |
| 申请号 |
SK20010001817 |
申请日期 |
2000.05.23 |
| 申请人 |
NASTECH PHARMACEUTICAL CO., INC. |
发明人 |
ACHARI RAJA G.;BEHL CHARANJIT R.;DEMEIRELES JORGE C.;DUA RAMNEIK ROMEO VINCENT D. - (DI);SILENO ANTHONY P. |
| 分类号 |
C07D489/02;A61F13/00;A61K9/00;A61K9/06;A61K9/08;A61K9/10;A61K9/14;A61K9/58;A61K31/44;A61K31/485;A61K47/10;A61K47/12;A61K47/14;A61K47/18;A61K47/20;A61K47/24;A61K47/28;A61K47/32;A61K47/34;A61K47/36;A61K47/38;A61K47/44;A61K47/46;A61P25/04;(IPC1-7):A61K31/44 |
主分类号 |
C07D489/02 |
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