| 摘要 |
<p>In detecting a genetic polymorphism by using a mass spectroscopic instrument, a genomic DNA containing the target polymorphism can be selected from a DNA sample on a substrate and bonded to the substrate by bonding an oligonucleotide hybridizable with the genomic DNA containing the target polymorphism to the substrate and then applying the genomic DNA sample to the substrate. Thus, it is found out that a target polymorphism can be more efficiently detected thereby. According to this method, polymorphisms in a large number of specimens can be quickly and comprehensively detected.</p> |
