PROTEINS, GENES AND THEIR USE FOR DIAGNOSIS AND TREATMENT OF CHRONIC ASTHMA

摘要

The present invention provides methods and compositions for screening, diagnosis and prognosis of chronic asthma, for monitoring the effectiveness of chronic asthma treatment, and for drug development. Chronic Asthma-Associated Features (CAFs), detectable by two-dimensional electrophoresis of tissue are described. The invention further provides Chronic Asthma-Associated Protein Isoforms (CAPIs) detectable in tissue preparations comprising isolated CAPIs, antibodies immunospecific for CAPIs, and kits comprising the aforesaid.