发明名称 |
Beta-hydroxybutyric acid or acetoacetic acid or salts or esters therof for use in improving cerebral function |
摘要 |
<p>A cerebral function improving agent containing as the active ingredient a compound represented by the following formula: <CHEM> wherein R2 represents a hydrogen atom when R1 is a hydroxyl group; or R1 and R2 are combined together to form an oxo group; R3 represents a hydrogen atom, an alkali metal, or a monohydric, dihydric or trihydric alcohol residue, which may be an oligomer composed of 2-10 molecules when R1 represents a hydroxyl group and R2 and R3 represent hydrogen atoms. The agent supresses cerebral edema, protects cerebral function, impaired cerebral energy metabolism, and reduces the extent of cerebral infarction.</p> |
申请公布号 |
EP0780123(B1) |
申请公布日期 |
2002.06.12 |
申请号 |
EP19960118764 |
申请日期 |
1996.11.22 |
申请人 |
BTG INTERNATIONAL LIMITED |
发明人 |
HIRAIDE, ATSUSHI, M.D.;DOHI, SEKIKO, PH.D.;SUZUKI, MOTOHISA;SHIBA, YOSHIHIRO |
分类号 |
A61K31/19;A61K31/22;A61P3/00;A61P9/00;A61P9/10;A61P25/00;(IPC1-7):A61K31/191 |
主分类号 |
A61K31/19 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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