发明名称 |
Homologous 28-kilodalton immunodominant protein genes of ehrlichia canis and uses thereof |
摘要 |
The present invention is directed to the cloning, sequencing and expression of homologous immunoreactive 28-kDa protein genes, ECa28-1 and ECa28SA3, from a polymorphic multiple gene family of Ehrlichia canis. A complete sequence of another 28-kDa protein gene, ECaSA2, is also provided. Further disclosed is a multigene locus encoding all five homologous 28-kDa protein genes of Ehrlichia canis. Recombinant Ehrlichia canis 28-kDa proteins react with convalescent phase antiserum from an E. canis-infected dog.
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申请公布号 |
US6403780(B1) |
申请公布日期 |
2002.06.11 |
申请号 |
US19990261358 |
申请日期 |
1999.03.03 |
申请人 |
RESEARCH DEVELOPMENT FOUNDATION |
发明人 |
WALKER DAVID H.;YU XUE-JIE;MCBRIDE JERE W. |
分类号 |
C07K14/29;(IPC1-7):C12N15/00;C12N1/20;C12N1/14;C12N1/16 |
主分类号 |
C07K14/29 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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