摘要 |
<p>alpha-Substituted carboxylic acid derivatives represented by general formula (I), pharmacologically acceptable salts of the same, or pharmacologically acceptable esters or amides thereof, which are useful as therapeutic and/or preventive agents for diabetes, impaired glucose tolerance, diabetes in pregnancy, and so on; wherein R1 is alkyl or the like; R2 is hydrogen or the like; R3 is hydrogen or the like; A is =CH- or the like; B is oxygen or the like; W1 is C1-C8 alkylene; W2 is a single bond or C1-C8 alkylene; X is hydrogen or the like; Y is oxygen or the like; and Z1 is alkoxy or the like.</p> |