发明名称 |
Process for the preparation of 1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)-methyl)-4H-carbazol-4-one |
摘要 |
<p>Pure 1,2,3,9-tetrahydro-9-methyl-3-Ä(2-methyl-1H-imidazol-1-yl)methylÜ-4H-c arbazol-4-one or a pharmaceutically acceptable salt thereof is prepared in a high yield by a simple process which reacts 1,2,3,9-tetrahydro-9-methyl-4H-carbazol-4-one with a 2-methylimidazole derivative in an organic solvent or in a mixture of an organic solvent and water in the presence of a halosilane compound.</p> |
申请公布号 |
EP1207160(A1) |
申请公布日期 |
2002.05.22 |
申请号 |
EP20010126998 |
申请日期 |
2001.11.14 |
申请人 |
HANMI PHARM. CO., LTD. |
发明人 |
LEE, KWANG-OK;KIM, MAENG-SUP;JUNG, KUM-SIN;KIM, HEE-SEOCK;KIM, HAN-KYENG;LEE, HOE-CHUL;HAM, YOUNG-JIN;KIM, CHEOL-KYEUNG;KIM, KI-EUN;LEE, GWAN-SUN |
分类号 |
C07D231/12;A61K31/4178;A61P1/08;C07D209/88;C07D233/58;C07D403/06;C07D521/00;(IPC1-7):C07D403/06 |
主分类号 |
C07D231/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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